Seralini is trying to overturn the consensus, and is so far failing. Answers to the main criticisms of the genetically modified gm nk603 maize and roundup study. New analysis of a rat feeding study with a gmo seralini. The scientific analysis in this document shows the research design that seralini et al. It probably has, but if so, its rare enough that i have never heard about it. A scientific analysis of the rat study conducted by gilles.
Gm corn nk603 the study long term toxicity of a roundup herbicide and a rounduptolerant genetically modi. An integrated multiomics analysis of the nk603 roundup. Control samples had the most distinct proteome and metabolome pro files as observed in pca plots. Longterm toxicity of a roundup herbicide and a roundup. Comprehensive further details about this group are available from laffaire seralini tag at this blog. The varieties of maize used in this study were the rtolerant nk603. Relevance of a new scientific publication mesnage et al. The health effects of a rounduptolerant genetically modified maize from 11% in the diet, cultivated with or without roundup, and roundup alone from 0.
European food safety authority denounces seralinis antigm food study n fly maggots that clean wounds and kill drug resistant germs will soon be the norm in the biomedical world and kari. Meanwhile, the serious implications for public health have been disregarded by monsanto, the critics and the regulators. The european food safety authority efsa evaluated the study as defective based on conceptual and methodological shortcomings by retroactive application of the recommendations of its recent guidance on 90day. This article is about the 2012 seralini study and the brouhaha around it. Seralini study is given new life, but wheres the new data. A recent paper published in the journal food and chemical toxicology presents the results of a longterm toxicity study related to a widelyused commercial herbicide roundup and a rounduptolerant genetically modified variety of maize, concluding that both the herbicide and the maize varieties are toxic. After several months of consumption of an rtolerant soy, the liver and pancreas of mice were affected, as highlighted by disturbances in subnuclear structure malatesta et al. A 2012 paper from the seralini criigen university of caen auchan carrefour greenpeace consortium published in food and chemical toxicology, retracted by the publisher in nov 20, has attracted a lot of attention to the topic of gm food safety.
Second submission to the productivity commission inquiry. Our data show that the signs of liver and kidney toxicity seen at 90 days from theconsumption of nk603 gm maize 3, 7 do indeed escalate into severe disease over an extended period. The publication of the study by the french biologist showing the devastating effects of glyphosate caused a shock wave at monsanto and the company has not stopped denouncing the publication by all means possible. By gm watch, editors decision violates scientific publication ethics. A study into longterm observational data by seralini shows that gm bt176 maize is most probably toxic in animals but the paper has since disappeared. Here we discuss the many errors and inaccuracies in the published article resulting. Does the seralini corn study fiasco mark a turning point in the debate over gm food. On the basis of the many scientific deficiencies identified in the study, fsanz does not accept the conclusions made by the authors and has therefore found no justification to reconsider the safety of nk603 corn, originally approved in 2002. Nk603 gm maize because r tolerance is the trait present in approximately 80% of agricultural gmos james, 2011 and because statistical differences in the 90day feeding trial with this maize were admitted to by both the petitioner and regulatory agencies efsa, 2009. The research team divided 200 rats 100 male, 100 female into groups of 10. It is the mirror piece of science that triggered seralinis investigation. The journal food and chemical toxicology fct wants to withdraw the article by professor seralini on rats fed gm maize nk603, which was published in september 2012. Furthermore,similar negative health effects were observed in all treatment groups nk603 gm maizewith or without r application and r alone.
In a followup chronic toxicity, investigation rats were fed the same nk603 gm corn for a 2year period. This article discusses a study published in scientific reports entitled an integrated multiomics analysis of the nk603 rounduptolerant gm maize reveals metabolism. In an effort to obtain deeper insight into these findings, molecular profiling of the liver and kidneys from the same animals was undertaken. This article is not about whether food from gmos is safe nor whether regulatory requirements are strict enough, and those issues should not be recapitulated here. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. The study was originally published in the elsevier journal food and chemical toxicology fct in september 2012, and caused global outcry and alarm in a number of countries who cited the study findings as reason for banning the import of genetically modified organisms. In that brief, abne clearly articulated views by experts and competent national and international food safety authorities on the study, all of which concluded that the study is seriously flawed in many. Nk603 and subcombinations independently of their origin, for food and feed uses, import and processing submitted under regulation ec no 18292003 by monsanto company. Public perception on labeling of genetically modified gm. Edoc interactive gmo maize and roundup the heat is on. Long term toxicity of a roundup herbicide and a rounduptolerant genetically modi. Scienceafrica journalist european food safety authority.
Rat feeding studies with genetically modified maize a. , emilie claira, robin mesnagea, steeve gressa, nicolas defargea, manuela malatestab, didier hennequinc, joel spiroux de vendomoisa a university of caen, institute of biology, criigen and risk pole, mrshcnrs, ea 2608, esplanade de la paix, caen cedex 14032, france. Responses from international scientists supporting seralini s work. Russia and kazakhstan have since halted imports of nk603 maize and, more recently, the kenyan cabinet has issued a directive to stop the import of gm foods due to inadequate research done on gmos and lack of scientific. For each sex, one control group of ten rats was given access to plain water and a standard diet from the closest isogenic nongm nk603, either treated or nontreated with roundup herbicide, to simulate the presence of roundup residues that are found in the maize. The feeding trial i will discuss on spraguedawley rats same rat strain as seralinis by hammond et. He used this study to call into question the safety of. The paper was published in 2012 in food and chemical toxicity. Followup on controversial gm maize study by seralini et al. A previous 2year rat feeding trial assessing potential toxicity of nk603 rounduptolerant genetically modified maize revealed blood and urine biochemical changes indicative of liver and kidney pathology. Conclusiveness of toxicity data and double standards.
A 2year rat feeding study with genetically modified nk603 maize sparked an international scientific and public debate as well as policy responses by the european commission. What are some of the lessons that journal editors can draw from this episode. I joined 120 scientists to sign a letter seralini and science. Glyphosate tolerant genetically modified gm maize nk603 was assessed as substantially equivalent to its isogenic counterpart by a nutrient. These are the conclusions of separate and independent assessments carried out by the european food safety authority efsa and six eu member states. First published by food and chemical toxicology in september 2012, the article presented a twoyear feeding study in rats, and reported an increase in tumors among rats fed genetically modified corn and the herbicide roundup. That article was subsequently retracted by the journal publisher, followed by an explanatory note from. Submitted by food democracy now on november 28, 20 2.
Long term toxicity of a roundup herbicide and a roundup. In this study researchers led by gilleseric seralini from criigen have found that rats fed on a diet containing nk603 roundup tolerant gm maize or given water containing roundup, at levels permitted in drinking water and gm crops in the us, developed cancers faster and died earlier than rats fed on a. There are few differences in composition between nk603 corn and its conventional counterpart. Control samples had the most distinct proteome and metabolome profiles as observed in pca plots. Jon entine contributor opinions expressed by forbes contributors are their own.
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